Ειρήνη Ελευθερίου ΠΑΙΔΙΑΤΡΟΣ Αναπληρώτρια Διευθύντρια της Παιδιατρικής Κλινικής

Αξιολόγηση μοριακών βιοδεικτών για τη διάκριση μεταξύ βακτηριακών και ιογενών λοιμώξεων σε παιδιά με πυρετό

European Society for Paediatric Infectious Diseases (ESPID)

• Συντονιστής Παιδιατρικών ΤΕΠ, Νοσοκομείο «ΜΗΤΕΡΑ»

• Μονάδα Λοιμώξεων, Β’ ΠΑΙΔΙΑΤΡΙΚΗ ΚΛΙΝΙΚΗ, ΕΚΠΑ – ΝΟΣΟΚΟΜΕΙΟ ΠΑΙΔΩΝ «Π. & Α. ΚΥΡΙΑΚΟΥ»

ΕΚΠΑΙΔΕΥΤΙΚΗ ΠΕΙΡΑ:

• Εκπαίδευση προπτυχιακών φοιτητών Ιατρικής ΕΚΠΑ (2016-2023)

• Μεταπτυχιακό Πρόγραμμα Σπουδών «Παιδιατρικές Λοιμώξεις», ΕΚΠΑ

• Μεταπτυχιακό Πρόγραμμα Σπουδών «Σύγχρονη πρόληψη και αντιμετώπιση παιδιατρικών νοσημάτων», Πανεπιστήμιο Θεσσαλίας

Κλινικό ενδιαφέρον:

• Παιδιατρικές λοιμώξεις 

Ερευνητικό ενδιαφέρον:

• Παιδιατρικές λοιμώξεις

• Tan CD, Vermont CL, Zachariasse JM, von Both U, Carrol ED, Eleftheriou I, Emonts M, van der Flier M, Herberg J, Kohlmaier B, Levin M, Lim E, Maconochie IK, Martinon-Torres F, Nijman RG, Pokorn M, Rivero-Calle I, Rudzāte A, Tsolia M, Zenz W, Zavadska D, Moll HA; PERFORM consortium (Personalised Risk assessment in febrile children to optimise Real-life Management across the European Union). Which low urgent triaged febrile children are suitable for a fast track? An observational European study. Emerg Med J. 2024 Mar 21;41(4):236-241. doi: 10.1136/emermed-2023-213375. PMID: 38238066; PMCID: PMC10982627.

• Lampidi S, Maritsi D, Charakida M, Eleftheriou I, Farmaki E, Spyridis N, Charisi K, Vantsi P, Filippatos F, Skourti K, Papadopoulou-Alataki E, Papadopoulou-Legbelou K, Kampouridou P, Grivea IN, Vergadi E, Gkentzi D, Dimou D, Koletsi P, Fotis L, Liakopoulou T, Agrafiotou A, Kourtesi K, Tsolas G, Kafetzis D, Papaevangelou V, Dimitriou G, Galanakis E, Syrogiannopoulos GA, Spoulou V, Michos A, Roilides E, Tsolia MN. Multisystem inflammatory syndrome in children (MIS-C): A nationwide collaborative study in the Greek population. Eur J Pediatr. 2024 Apr;183(4):1693-1702. doi: 10.1007/s00431-023-05383-5. Epub 2024 Jan 12. PMID: 38214810; PMCID: PMC11001744.

• Jackson HR, Zandstra J, Menikou S, Hamilton MS, McArdle AJ, Fischer R, Thorne AM, Huang H, Tanck MW, Jansen MH, De T, Agyeman PKA, Von Both U, Carrol ED, Emonts M, Eleftheriou I, Van der Flier M, Fink C, Gloerich J, De Groot R, Moll HA, Pokorn M, Pollard AJ, Schlapbach LJ, Tsolia MN, Usuf E, Wright VJ, Yeung S, Zavadska D, Zenz W, Coin LJM, Casals-Pascual C, Cunnington AJ, Martinon-Torres F, Herberg JA, de Jonge MI, Levin M, Kuijpers TW, Kaforou M; PERFORM consortium. A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study. Lancet Digit Health. 2023 Nov;5(11):e774-e785. doi: 10.1016/S2589-7500(23)00149-8. PMID: 37890901.

• Shah P, Voice M, Calvo-Bado L, Rivero-Calle I, Morris S, Nijman R, Broderick C, De T, Eleftheriou I, Galassini R, Khanijau A, Kolberg L, Kolnik M, Rudzate A, Sagmeister MG, Schweintzger NA, Secka F, Thakker C, van der Velden F, Vermont C, Vincek K, Agyeman PKA, Cunnington AJ, De Groot R, Emonts M, Fidler K, Kuijpers TW, Mommert-Tripon M, Brengel-Pesce K, Mallet F, Moll H, Paulus S, Pokorn M, Pollard A, Schlapbach LJ, Shen CF, Tsolia M, Usuf E, van der Flier M, von Both U, Yeung S, Zavadska D, Zenz W, Wright V, Carrol ED, Kaforou M, Martinon-Torres F, Fink C, Levin M, Herberg J; PERFORM consortium. Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study. Lancet Reg Health Eur. 2023 Jul 26;32:100682. doi: 10.1016/j.lanepe.2023.100682. PMID: 37554664; PMCID: PMC10405323.

• Jackson HR, Miglietta L, Habgood-Coote D, D’Souza G, Shah P, Nichols S, Vito O, Powell O, Davidson MS, Shimizu C, Agyeman PKA, Beudeker CR, Brengel-Pesce K, Carrol ED, Carter MJ, De T, Eleftheriou I, Emonts M, Epalza C, Georgiou P, De Groot R, Fidler K, Fink C, van Keulen D, Kuijpers T, Moll H, Papatheodorou I, Paulus S, Pokorn M, Pollard AJ, Rivero-Calle I, Rojo P, Secka F, Schlapbach LJ, Tremoulet AH, Tsolia M, Usuf E, Van Der Flier M, Von Both U, Vermont C, Yeung S, Zavadska D, Zenz W, Coin LJM, Cunnington A, Burns JC, Wright V, Martinon-Torres F, Herberg JA, Rodriguez-Manzano J, Kaforou M, Levin M. Diagnosis of Multisystem Inflammatory Syndrome in Children by a Whole-Blood Transcriptional Signature. J Pediatric Infect Dis Soc. 2023 Jun 30;12(6):322-331. doi: 10.1093/jpids/piad035. PMID: 37255317; PMCID: PMC10312302.

• Dimopoulou D, Dasoula F, Liaska M, Eleftheriou I, Maritsi D, Tsolia M, Vartzelis G. Rise of Neurologic Manifestations During SARS-CoV-2 Omicron Wave in Children With COVID-19.Pediatr Infect Dis J. 2023;42(4):e128-e129. doi:10.1097/INF.000000000000382

• Nijman RG, Tan CD, Hagedoorn NN, Nieboer D, Herberg JA, Balode A, von Both U, Carrol ED, Eleftheriou I, Emonts M, van der Flier M, de Groot R, Kohlmaier B, Lim E, Martinón-Torres F, Pokorn M, Strle F, Tsolia M, Yeung S, Zachariasse JM, Zavadska D, Zenz W, Levin M, Vermont CL, Moll HA, Maconochie IK; PERFORM consortium. Are children with prolonged fever at a higher risk for serious illness? A prospective observational study. Arch Dis Child. 2023 Aug;108(8):632-639. doi: 10.1136/archdischild-2023-325343. Epub 2023 Apr 25. PMID: 37185174.

• Eleftheriou I, Maritsi D, Lampidi S, Charisi K, Vantsi P, Skourti K, Filippatos F, Amplianitis I, Dimou D, Papadopoulou-Legbelou K, Papadopoulou-Alataki E, Kampouridou P, Koletsi P, Fotis L, Vergadi E, Gkentzi D, Farmaki E, Papaevangelou V, Galanakis E, Grivea IN, Syrogiannopoulos GA, Spoulou V, Spyridis N, Michos A, Roilides E, Tsolia MN. Decreasing Incidence of the Multisystem Inflammatory Syndrome in Children Over 3 Pandemic Waves. Pediatr Infect Dis J. 2023;42(2):122-124. doi:10.1097/INF.0000000000003766

• van der Velden FJS, de Vries G, Martin A, Lim E, von Both U, Kolberg L, Carrol ED, Khanijau A, Herberg JA, De T, Galassini R, Kuijpers TW, Martinón-Torres F, Rivero-Calle I, Vermont CL, Hagedoorn NN, Pokorn M, Pollard AJ, Schlapbach LJ, Tsolia M, Elefhteriou I, Yeung S, Zavadska D, Fink C, Voice M, Zenz W, Kohlmaier B, Agyeman PKA, Usuf E, Secka F, de Groot R, Levin M, van der Flier M, Emonts M; PERFORM consortium. Febrile illness in high-risk children: a prospective, international observational study. Eur J Pediatr. 2023 Feb;182(2):543-554. doi: 10.1007/s00431-022-04642-1. Epub 2022 Oct 15. Erratum in: Eur J Pediatr. 2023 Feb;182(2):555-556. doi: 10.1007/s00431-022-04788-y. PMID: 36243780; PMCID: PMC9899189.

• Tan CD, van der Walle EEPL, Vermont CL, von Both U, Carrol ED, Eleftheriou I, Emonts M, van der Flier M, de Groot R, Herberg J, Kohlmaier B, Levin M, Lim E, Maconochie IK, Martinon-Torres F, Nijman RG, Pokorn M, Rivero-Calle I, Tsolia M, Yeung S, Zenz W, Zavadska D, Moll HA; PERFORM consortium (Personalised Risk assessment in febrile children to optimize Real-life Management across the European Union). Guideline adherence in febrile children below 3 months visiting European Emergency Departments: an observational multicenter study. Eur J Pediatr. 2022 Dec;181(12):4199-4209. doi: 10.1007/s00431-022-04606-5. Epub 2022 Sep 30. Erratum in: Eur J Pediatr. 2022 Dec;181(12):4211-4214. doi: 10.1007/s00431-022-04664-9. PMID: 36178539; PMCID: PMC9649464.