Sofia-Melina Stasinou OBSTETRICIAN - GYNECOLOGIST, OBSTETRICIAN – GYNECOLOGIST

• PhD thesis in “Evaluation of Obstetric Analgesia”, Department of Obstetrics and Gynecology of University Medical School of Ioannina, Ioannina, Greece (2013)

POSTGRADUATE QUALIFICATIONS:

• March 2011: Master of Science Degree (MSc) in “Research in women reproduction” in University of Athens, Aretaieion Hospital. The subject of postgraduate study: “Retrospective observational study of placenta tissues with vascular lesions in association with pregnancy outcomes.” Aretaieion Hospital of Athens (29/11/2011) Registration No: 1015

• April 2012: Member of the Working Group of the National Program for the Cervical Cancer Screening, co-financed by the European Union and implemented by the Ministry for Health and Social Solidarity (Decision of the Secretary-General for Health and Social Solidarity File No: ΔΥ1δ/οικ 34217)

• June 2012: PhD thesis in “Evaluation of Obstetric Analgesia”, Department of Obstetrics and Gynecology of University Medical School of Ioannina, Ioannina, Greece (20/02/2013)

• 2015: Embryo transfer/IUI and Pelvic transvaginal ultrasound Certification (British Fertility Society, London, UK)

• 2018: Marion Gluck Academy Training graduation Level 2 (Bio-identical Hormonal Replacement Treatment)

• July 2019: Assistant Professor of Clinical Obstetrics & Gynaecology Weill Cornell Medicine -Q

• August 2019: Fellowship in Functional Gynaecology (International Association of Aesthetic Gynaecology and Sexual Wellbeing)

COURSES:.

• Colposcopy: Theoretical and practical hands-on Course in the framework of 9^th European Seminar of Colposcopy & Cervical Pathology, 17&18 June 2011, Athens, Greece (5 CPD)

• Diagnostic and Operative Hysteroscopy Pre-congress Course, 11-12^th May 2011, Department of Obstetrics and Gynaecology University Hospital of Ioannina, Greece (5 CPD)

• Basic Colposcopy course: Hands-on course, pre-congress workshop (14^th June 2012-Iaso Private Clinic) in the framework of the 10^th European Colposcopy and Cervical Pathology Congress, 15-16 June 2012, Athens, Greece (5 CPD)

• Course Information Governance Foundation Training (07 Feb 2013)

• British Fertility Society Master Class in Reproductive Surgery, Clinical Skills Centre, Northern General Hospital, Sheffield (10 Jan 2014)

• British Fertility Society Course for Ultrasound, Embryo Transfer and IUI certification (2-4^th June 2014)

• Course of HyCoSy, SIS and 3D Gynaecological Course 14^th-15^th June 2014, Guy’s Hospital  (12 CPD)

• Marion Gluck Training Academy (Bio-identical Hormonal Replacement Treatment (course 1 and 2 completed) (October 2018)

• Basic Life support training (BLS) 24 January 2019

• Neonatal Resuscitation Training (NRP) 31^st January 2019

• Advanced Life Support in Obstetrics (ALSO) July 2019

• Immediate Life Support (ILS) September 2019

• Fellowship in Aesthetic Gynaecology Surgical & non-Surgical (IAAGSW), August 2019

• Member of British Society of Colposcopy and Cervical Pathology for diagnostic and treatment colposcopy modules (BSCCP) (logbook completed) (17/07/2012)

• Member of ISMAAR (The International Society for Mild Approaches in Assisted Reproduction)

• Member of British Fertility Society (BFS)

• Member of European Society of Human Reproduction (ESHRE)

• Associate Member of Royal College of Obstetricians and Gynaecologists, UK

• Member of Cochrane Gynaecologic Cancer Group

• Member of the Working Group of the Hellenic National Program for the Cervical Cancer Screening (April 2012)

• Member of Hellenic Cervical Pathology Academic Study Group (HeCPA study Group)

• Member of American Society of Reproductive Medicine (ASRM)

• Member of American Cell Medicine and Official Provider of O-Shot treatment

AD-HOC REVIEWER for peer-reviewed international journals

• Journal of Radiology

• Rubriq (peer-reviewed journal from USA)

• Plos One Peer reviewed journal

• Reviewer for WORLD CONGRESS of RCOG 2019

• Reviewer for WORLD CONGRESS of RCOG 2020

05/01/2019- till present:

• Private Obstetrician & Gynecologist Athens, Greece

• MITERA HOSPITAL (external collaboration with IVF MITERA)

• Assistant Professor of Clinical Obstetrics and Gynecology Weill Cornell Medicine

09/2013-12/2018: Senior Consultant in Reproductive Medicine, Leading doctor in Advanced Ultrasound, Techniques, Create Fertility, London, UK

28/08/2012- 08/2013: Post CCT Research Fellow IVF Hammersmith, Imperial College, London, UK

16/07/2009 – 28/11 2012  Specialist Registrar post at the Department of Obstetrics and Gynaecology at General University Hospital of Ioannina, Ioannina, Greece

16/04/2008 – 16/07/2009 SHO-Specialty Training post in the Department of Gynaecology at the General Hospital of “G. Gennimatas”, Athens, Greece

01/10/2006 – 16/05/2007 SHO in the Department of Urology at General Hospital of Mytilini, Greece.

22/09/2005 –30/09/2006 Specialty Training post in the Department of General Surgery at General Hospital of Mytilini, Lesvos Island, Greece

09/02/2004 – 20/02/2005 Compulsory post as a Rural General Practitioner in Public Health Centre Kalloni, Lesvos Island, Greece

03/11/2003 – 02/02/2004 Clinical Rotation as Specialty Training post (SHO) in the Departments of Internal Medicine, Cardiology and General Surgery at General Hospital of Mytilini, Greece

• Gynecology

• Gynecological endocrinology

• Male and Female Infertility

• Functional Gynecology

• Vaginal Rejuvenation

• Hormonal Imbalance

Research:

The focus of my research naturally mirrors my clinical responsibilities: obstetric analgesia, cervical pathology in relation to pregnancy outcomes and infertility.   Although the grant funding in my country has been modest, through the Hellenic Academic Group of Cervical Pathology, I have managed to contribute in quite a number of clinical studies important to this field which have been awarded abroad. In particular, I have participated in investigating the proportion of the cervical excision and the relation with the pregnancy outcome; the fertility and the pregnancy outcomes after treatment for cervical intraepithelial neoplasia; the accuracy of the new technology of biospectroscopy analysis to identify underlying disease comparing with the conventional cervical screening; the evaluation of HPV biomarkers and their significance for women that need cervical intervention. I have contributed to the introduction of intracellular HPV E6/E7 mRNA expression in cervical cancer screening programs with flow cytometry assay in Greek women and the evaluation of p16/ki67 dual-stain cytology as a triage tool for ascus and Low Grade Squamous Intraepithelial Lesions cytology results. My review publication of the 22 years’ experience of the technique of the large loop excision of the transformation zone in cervical intraepithelial neoplasia has reached more 150 citation worldwide (https://www.researchgate.net). Furthermore, I am regularly invited to speak to relevant congresses and share my research and also as a reviewer, to evaluate articles and abstracts for journals and national and international congresses (official reviewer for RCOG 2019, 2020). Recently, as a faculty member of WCM-Q I have contributed as Principle Investigator to the grant application (NPRP 13S-0114-200066) with the title: Diet effect on the Follicular Cells Metabolism: towards Personalized Nutrition in Assisted Reproductive Technologies (2021-2023).

• Award for one of the 10 Best Oral Presentations at the Annual Scientific Meeting of the BSCCP, March 30^th – April 1^st 2011, Liverpool, UK. “Effect of Condom Use After CIN treatment on HPV Positivity: A Randomised Clinical trial”

• 1^st Prize Award for the Best Oral Free Presentation at the 9^th International Scientific Meeting of the Royal College of Obstetricians and Gynaecologists (RCOG) 28-30 September 2011, Athens, Greece. “Expression of HPV-related biomarkers in association with the grade of cervical intraepithelial lesion”

• 1^st Prize Award for the Best Oral Free Presentation at the International Course in Colposcopy and Cervical Pathology, November 10^th-12^th, 2011,” Karolos Papoulias” Ioannina, Greece. “Long-term data on the trend of HPV-related biomarkers post-treatment for cervical intra-epithelial lesions”

• 1^st Prize Award for the Best Oral Presentation at the 5^th Pancretian Congress of Obstetrics and Gynaecology, March 31^st – April 1^st, 2012, Heraklion, Crete, Greece

• 1^st Prize Award for two of the 10 Best Oral Presentations at the Annual Scientific    Meeting of the BSCCP, April 18^th-20^th 2012, Newcastle, UK. “Alterations on HPV-related biomarkers after prophylactic HPV vaccination” and “Follow-up of untreated high-grade lesions: is there a role for surveillance with HPV-related biomarkers?”

• 1^st Prize Award for the Best Oral Presentation at the Annual Scientific Meeting of the BSCCP, April 18^th-20^th 2012, Newcastle, UK. “Proportion of excision, cervical healing and pregnancy outcomes after Large Loop Excision of the Transformation Zone for Cervical Intraepithelial Neoplasia”

BOOK CHAPTERS:

“Vascular disorders of placenta” Guide for trainees in the Department of Pathology 2012, Aretaieion University Hospital of Athens, Greece

(RG score 17.48; h-index 4)

• Proportion of cervical excision for CIN as a predictor of pregnancy outcomes: A prospective study. Maria Kyrgiou, G. Valasoulis, Sofia Melina Stasinou et al. ( January 2015)

• Fertility and early pregnancy outcomes after treatment for cervical intraepithelial neoplasia: systematic review and meta-analysis. (BMJ Clinical Research 10/2014). Maria Kyrgiou, Anita Mitra, Marc Arbyn, Sofia Melina Stasinou et al

• Proportion of cervical excision for cervical intraepithelial neoplasia as a predictor of pregnancy outcomes (International Journal of Gynaecology & Obstetrics 10/2014) Maria Kyrgiou, George Valasoulis, Sofia-Melina Stasinou et al.

• Histology Verification Demonstrates That Biospectroscopy Analysis of Cervical Cytology Identifies Underlying Disease More Accurately than Conventional Screening: Removing the Confounder of Discordance (PLoS ONE 02/2014) Gajjar K. et al. ,

• Congenital Nephrotic Syndrome of the Finnish Type:A Greek Case Report (Health 01/2014) Sofia Melina Stasinou et al.

• Expression of HPV-related biomarkers and grade of cervical intraepithelial lesion at treatment (Acta Obstetricia et Gynecologica Scandinavica 10/2013) George Valasoulis, Sofia-Melina Stasinou et al.

• Large loop excision of the transformation zone and cervical intraepithelial neoplasia: a 22- year experience (Anticancer research 09/2012) Sofia Melina Stasinou et al.

• Management of low-grade squamous intra-epithelial lesions of the uterine cervix: repeat cytology versus immediate referral to colposcopy (Cochrane.Database.Syst.Rev. 01/2012) Kyrgiou, Sofia Melina Stasinou et al.