Konstantinos Papaspyrou OTOLARYNGOLOGIST

6984 463 463
210 686 7856
kpapaspyrou@hygeia.gr
konpapasp@yahoo.com

Education & Academic Qualifications

09/1997: Admission to Faculty of Medicine, National & Kapodistrian University of Athens
02/2004: Graduation from Faculty of Medicine, National and Kapodistrian University of Athens, marked with “Very Good”
05/07/2004-31/07/2012: ENT Specialty, PhD Thesis and salaried position as ENT Specialist/Registrar after acquiring the ENT Specialty, ENT Clinic, University of Mainz, Germany (Director: Univ.-Prof. Dr. med. Dr. h. c. mult. Wolf J. Mann)

Special Training (Courses/Workshops/Hands-on Experience):

Stimmrehabilitation nach Laryngektomie mittels stimmprothetischer Versorgung (“Voice rehabilitation after laryngectomy with voice prostheses”), University of Mainz, ENT Clinic, Mainz, Germany, 16/10/2004.
Mainzer Ultraschallkurse fur HNO-Arzte und Kieferchirurgen 2005, (Postgraduate ultrasound seminars for ENT & Maxillofaxial surgeons), University of Mainz, ENT Clinic, Mainz, Germany (Continuing Medical Education, Credits 63)
International Workshop on Micro-Endoscopic Sinus Surgery, University of Mainz, ENT Clinic, Mainz, Germany, 02-04/06/2005 (Continuing Medical Education, Credits 23)
International Workshop on Micro-Endoscopic Sinus Surgery, University of Mainz, ENT Clinic, Mainz, Germany, 02- 04/03/2006 (Continuing Medical Education, Credits 23)
6th Wullstein Symposium, (Symposium on Ear Surgery and Cochlear Implantation), Wurzburg, Germany, 7-12/12/2006
Mainzer Ultraschallkurse fur HNO-Arzte und Kieferchirurgen 2007, (Postgraduate ultrasound seminars for ENT & Maxillofaxial surgeons), University of Mainz, ENT Clinic, Mainz, Germany (Continuing Medical Education, Credits 63)
International Workshop on Micro-Endoscopic Sinus Surgery, University of Mainz, ENT Clinic, Mainz, Germany, 01-03/03/2007 (Continuing Medical Education, Credits 23)
Head & Neck Surgical Resection Workshop (Cadaver Dissection) ENT Department, Evangelismos General Hospital (excavation of temporal bone, nasal septum surgery, paranasal surgery (FESS), salivary gland surgery, larynx surgery, rhinoplasty, otoplasty), Experimental Operating Room, Evangelismos General Hospital, 10-16/03/2007
Mainzer Ultraschallkurse fur HNO-Arzte und Kieferchirurgen 2008, (Postgraduate ultrasound seminars for ENT & Maxillofaxial surgeons), University of Mainz, ENT Clinic, Mainz, Germany (Continuing Medical Education, Credits 63)
International Workshop on Micro-Endoscopic Sinus Surgery, University of Mainz, ENT Clinic, Mainz, Germany, 21-23/02/2008 (Continuing Medical Education, Credits 23)
12th Head & Neck Surgical Resection Workshop (Cadaver Dissection) ENT Department, Evangelismos General Hospital (excavation of temporal bone, nasal septum surgery, paranasal surgery (FESS), salivary gland surgery, larynx surgery, rhinoplasty, otoplasty), Experimental Operating Room, Evangelismos General Hospital, 15-21/03/2008
9th International Training Course on Endoscopic and Microscopic Sinus Surgery, Marburg, Germany, 31/08-02/09/2008
Rhino Days 2009, International Symposium on Nasal Obstruction and Balloon Sinuplasty, Marburg, Germany, 15-17/01/2009
14th Head & Neck Surgical Resection Workshop (Cadaver Dissection) ENT Department, Evangelismos General Hospital (excavation of temporal bone, nasal septum surgery, paranasal surgery (FESS), salivary gland surgery, larynx surgery, rhinoplasty, otoplasty), Workshop Lab, Evangelismos General Hospital, 07-12/03/2009
10th International Training Course on Endoscopic and Microscopic Sinus Surgery, Marburg, Germany, 30/08-01/09/2009
Mainzer Ultraschallkurse fur HNO-Arzte und Kieferchirurgen 2010, (Postgraduate ultrasound seminars for ENT & Maxillofaxial surgeons), University of Mainz, E.N.T. Clinic, Mainz, Germany (Continuing Medical Education, Credits 63)
15th Head & Neck Surgical Resection Workshop (Cadaver Dissection) ENT Department, Evangelismos General Hospital (excavation of temporal bone, nasal septum surgery, paranasal surgery (FESS), salivary gland surgery, larynx surgery, rhinoplasty, otoplasty), Workshop Lab, Evangelismos General Hospital, 19-21/03/2010
Mainzer Ultraschallkurse fur HNO-Arzte und Kieferchirurgen 2011, (Postgraduate ultrasound seminars for ENT & Maxillofaxial surgeons), University of Mainz, ENT Clinic, Mainz, Germany (Continuing Medical Education, Credits 63)
Kurs: Tracheoskopie und Bronchoskopie bei Kindern (Course: Tracheoscopy and Bronchoscopy in children), 11th Annual Meeting of the German Academy of Oto-Rhino-Laryngology, Head and Neck Surgery, 19-20/05/2012, Mainz, Germany, 19/05/2012
Kurs: Stridor und Atemwegsdiagnostik bei Sauglingen und Kindern (Course: Stridor and Airway Diagnostics in infants and children), 11th Annual Meeting of the German Academy of Oto-Rhino-Laryngology, Head and Neck Surgery, 19- 20/05/2012, Mainz, Germany, 20/05/2012

Doctoral thesis

“Immunohistochemical analsysis of the fascin expression in squamous cell carcinomas in the area of the head and neck” (Immunohistochemische Analyse der Fascinexpression in Platenepithelkarzinomen des Kopf-Hals-Bereiches), ENT Clinic, Johannes Gutenberg University, Mainz, Germany (07/2009)

Fellowship in Societies, Membership in Journal Editorial Committees

Fellowship in Societies:

Athens Medical Association
Hellenic Society for ENT-Head & Neck Surgery
Hellenic Society of Otology and Neurotology
Athens Medical Society
Hellenic Society for ENT-Allergy, Immunology & Snoring
European Rhinologic Society
German Society for ENT-Head & Neck Surgery (Deutsche Gesellschaft fur Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e.V.)
Greek Medical Association

Membership in Journal Editorial Committees:

Skull Base Reports
Head Neck
European Archives of Oto-Rhino-Laryngology and Head & Neck
Hormones Journal
World Journal of Surgical Oncology
Webmed Central
Endocrine-Related Cancer
Clinical Chemistry and Laboratory Medicine (CCLM)

Work Experience

05/07/2004-31/07/2012: Salaried position as ENT Specialist/Registrar after acquiring the ENT Specialty, ENT Clinic, University of Mainz, Germany (Director: Univ.-Prof. Dr. med. Dr. h. c. mult. Wolf J. Mann)
09/2012-03/2013: Military service – 13/10/2004-10/03/2013: Physician, Special Forces Train-ing Center, Nea Peramos, Attica, 124 Basic Training Unit, Tripoli (20/01-15/02/2013)
03/2013-currently: Private practice
03/2013-currently: Associate Physician, HYGEIA Hospital
08/2013-currently: Associate Physician, MITERA Hospital

Teaching Experience:

Teaching ENT classes to Medicine students, Johannes Gutenberg University, Mainz, Germany & oral examiner at the final exams for the specific class
Lectures in postgraduate classes, ENT University Clinic, Mainz, Germany
Participation as trainer in Mainzer Ultraschallkurse fur HNO-Arzte und Kieferchirurgen 2012/13 Grundkurs der Kopf- Halssonographie (Postgraduate ultrasound seminars for ENT & Maxillofaxial surgeons / Basic level), 29-30/06/2012, University of Mainz, ENT Clinic, Mainz, Germany.

Clinical & Research Interest

Clinical Interest:
Diagnostic Possibilities
Otology

Otoneurology
Hearing loss
Vertigo
Tinnitus
Acute deafness
Meniere’s disease
Indications for hearing aids
Acute otitis, secretory otitis, external otitis
Chronic otitis media, cholesteatoma
Traumatic tympanic membrane perforation
Otosclerosis
Facial serve palsy/paralysis

Rhinology

Snoring, Obstructive Sleep Apnea Syndrome
Nasal and paranasal polyps
Nasal septum deviation
Nasal turbinate hypertrophy
Allergic rhinitis
Acute/chronic sinusitis
Rhinorrhagia
Smell/taste disorders
Eustachian tube dysfunction

Laryngology

Larynx/vocal cord conditions
Hoarse voice
Phoniatrics
Vocal cord calluses, papillomas, polyps, leukoplakia
Upper respiratory breathing difficulty
Gastroesophageal/Laryngopharyngeal Reflux & Posterior laryngitis
Dysphagia/Difficulty swallowing liquids

Salivary gland conditions (parotid, submandibular gland)

Salivary gland neoplasms
Sialolithiasis

Pediatric ENT
Head & Neck Oncology Surgery

Benign & Malignant nasal/parasanal neoplasms
Benign & Malignant oral cavity/buccopharynx neoplasms
Benign & Malignant nasopharynx neoplasms
Benign & Malignant larynx/hypopharynx neoplasms
Cervical swelling

Other conditions

Tonsil conditions
Bad breath
Feeling of foreign object in neck
Adenoid hypertrophy
Frenulum linguae/upper lip

Surgical Procedures:

Cervical swelling
Open lymph node biopsy
Cervical excavation for removal of single swelling (branchial neck cyst, etc)
Lymph node dissection
Salivary Gland Surgery (parotid, submandibular gland) / Stone removal
Amygdalectomy
Oral cavity/buccopharynx tumors (surgical removal/biopsy)
Endoscopic adenectomy / Removal of adenoids
Phonosurgery
Vocal cord papillomas, polyps, cysts, nodules, granulomas, leukoplakia, calluses, Reinke’s edema with CO2 LASER
Vocal cord paralysis
Posterior cordotomy using the modified Kashima’s technique
Dilation material infusion in vocal cords
Larynx/hypopharynx cancer with CO2 LASER
Surgical treatment for snoring / sleep apnea
Laser-assisted uvulopalatoplasty (LAUP)
Uvulopalatopharyngoplasty (UPPP)
Lingual/upper lip frenectomy
Intratympanic injection (cortisone or gentamicin) in the middle ear for treatment of hearing loss, vertigo, tinnutus at doctor’s office
Eardrum paracentesis / ventilation tube insertion
Otosurgery
Tympanoplasty (chronic otitis, tympanic membrane perforation, cholesteatoma)
Mastoidectomy
Endoscopic nasal turbinate hypertrophy submucosal cauterization with Diode Laser at the doctor’s office
Endoscopic polyp removal from nasal cavities
Endoscopic nasal and paranasal surgery (Functional Endoscopic Sinus Surgery / FESS) for sinusitis, polyps
Endoscopic nasal septum deviation correction
Recurrent rhinorrhagia, e.g. Osler-Weber-Rendu syndrome, with Diode Laser at the doctor’s office
Endoscopic treatment of rhinorrhagia / cauterization or ligation of sphenopalatine artery
Endioscopic removal/biopsy of nasal/ paranasal/nasopharynx tumors
Placement of Montgomery prosthesis in trachea (in tracheal stenosis) and larynx (in thyroplasty due to vocal cord paralysis)
Tracheostomy

Most of these procedures are performed as:

One Day Surgery
Minimally Invasive Surgery

Research Interest:

Glomus Tumors of the head and neck (8 relevant articles in peer-reviewed foreign scientific journals)
Scientific posters in international conventions (18)
Scientific posters in Greek conventions (9)
Participation in Greek and foreign conventions (over 100)

Recent Publications

Papaspyrou K, Brochhausen C, Schmidtmann I, Fruth K, Gouveris H, Kirckpatrick J, Mann W, Brieger J., Fascin upregulation in primary head and neck squamous cell carcinoma is associated to lymphatic metastasis. Oncol Lett. 2014 Jun;7(6):2041-2046.
Bickmann JK, Sollfrank S, Schad A, Musholt TJ, Springer E, Miederer M, Bartsch O, Papaspyrou K, Koutsimpelas D, Mann WJ, Weber MM, Lackner KJ, Rossmann H, Fottner C. Phenotypic variability and risk of malignancy in SDHC-linked paragangliomas: lessons from three unrelated cases with an identical germline mutation (p.Arg133*). J Clin Endocrinol Metab. 2014 Mar;99(3):E489-96.
Papathomas TG, Gaal J, Corssmit EP, Oudijk L, Korpershoek E, Heimdal K, Bayley JP, Morreau H, van Dooren M, Papaspyrou K, Schreiner T, Hansen T, Andresen PA, Restuccia DF, van Kessel I, van Leenders GJ, Kros JM, Looijenga LH, Hofland LJ, Mann W, van Nederveen FH, Mete O, Asa SL, de Krijger RR, Dinjens WN. Non-pheochromocytoma (PCC)/paraganglioma (PGL) tumors in patients with succinate dehydrogenase-related PCC-PGL syndromes: a clinicopathological and molecular analysis. Eur J Endocrinol. 2013 Nov 22;170(1):1-12.
Papaspyrou K, Welkoborsky HJ, Gouveris H, Mann WJ. Malignant and benign sinonasal paragangliomas. Laryngoscope. 2013 Aug;123(8):1830-6.
Papaspyrou K, von Creytz H, Kolonko K, Mewes T, Mann W, Scharrer I. [Bleeding and coagulation disorders in tonsillectomies]. HNO. 2012 Jun;60(6):511-7. [Article in German]
Papaspyrou K, Mewes T, Rossmann H, Fottner C, Schneider-Raetzke B, Bartsch O, Schreckenberger M, Lackner KJ, Amedee RG, Mann WJ. Head and neck paragangliomas: Report of 175 patients (1989-2010). Head Neck. 2012 May;34(5):632-7.
Taeumer T, de Greiff A, Scharrer I, Papaspyrou K, Mewes T, Mann W. [The significance of bleeding disorders in patients with epistaxis]. HNO. 2011 Jun;59(6):582-7. [Article in German]
Papaspyrou K, Mewes T, Toth M, Schmidtmann I, Amedee RG, Mann WJ. Hearing results after hypotympanotomy for glomus tympanicum tumors. Otol Neurotol. 2011 Feb;32(2):291-6.
Papaspyrou K, Mann WJ, Amedee RG. Management of head and neck paragangliomas: review of 120 patients. Head Neck. 2009 Mar;31(3):381-7.
Papaspyrou K, Rossmann H, Fottner C, Weber MM, Mann W, Lackner KJ, Helling K. Malignant paraganglioma caused by a novel germline mutation of the succinate dehydrogenase D-gene–a case report. Head Neck. 2008 Jul;30(7):964-9.

A total of 15 articles in Greek and foreign scientific journals, 12 of which appeared in peer-reviewed foreign scientific journals (including Pubmed), 2 in peer-reviewed foreign scientific journals as cited abstracts and 1 in a Greek scientific journal, as well as 180 citations in international bibliography.