Polixeni Koutkia ENDOCRINOLOGIST Nutritional Medicine & Endocrine Clinic HYGEIA Hospital

T: 210 686 7186
p.koutkia@hygeia.gr

Education & Academic Qualifications

Academic Appointments:

2000-2002 Teaching Fellow in Medicine, Boston University School of Medicine
2002-2003 Postdoctoral Research Fellow in Medicine, Harvard Medical School
2004- 2006 Instructor in Medicine, Harvard Medical School

Hospital and Affiliated Institution Appointments:

2000-2002 Clinical Fellow, Department of Medicine, Boston Medical Center
2002- Research Fellow, Department of Medicine, Massachusetts General Hospital
2004-2006 Clinical Assistant in Medicine, Staff Neuroendocrine Unit, Massachusetts General Hospital, Boston, USA
2007- 2009 Director Endocrine &Metabolic Unit, Henry Dunant Hospital, Athens
2010 – Director Endocrine and Nutrition Unit, Hygeia Hospital, Athens Greece

Hospital and Service Responsibilities:

2002-2004 Director, Neuroendocrine Conference, Division of Endocrinology, Massachusetts General Hospital
9/2006- 2009 Director Endocrine and Metabolic Unit, Henry Dunant Hospital
2010 – Director Endocrine and Metabolic Unit, Hygeia Hospital, Athens Greece

Education:

1993 M.D. National and Kapodistrian University of Athens Medical School, Athens, Greece
1994 Medical License in Greece
1996 USA Educational Commission for Foreign Medical Graduates (ECFMG), permanent certification

Internships and Residencies:

1997-1998 Intern in Medicine, Rhode Island Hospital, Brown University,RI
1998-1999 Junior Resident in Medicine, Rhode Island Hospital,RI
1999-2000 Senior Resident in Medicine, Rhode Island Hospital,RI

Licensure and Certification:

1994 Medical License in Greece
1996 USA Educational Commission for Foreign Medical Graduates (ECFMG), permanent certification
1997-2000 Rhode Island Medical License Registration
2000-2006 Massachusetts License Registration
2001 Internal Medicine, American Board of Internal Medicine (ABIM)
2002 Endocrinology, Diabetes and Metabolism, American Board of Internal Medicine (ABIM)
2002 Certified in Training Laboratory Clinical Director, COLA
2002 Certified in Thyroid Ultrasound, Endocrine Society
2002 Clinical Densitometrist, International Society for Clinical DensitometryCertified. Radioactive iodine course in Nuclear Radiology, Brigham & Womens’ Hospital, Boston, MA
2004 Certified, American Board of Physician Nutrition Specialists
2006 Certified in Endocrinology, Greek Board of Endocrinology
2015 Recertification – Endocrinology, Diabetes and Metabolism, American Board of Internal Medicine ((10 year Recertification) ABIM

Doctoral thesis

2001-2003 M.A. Master of Arts in Clinical Investigation, Boston University, Boston, MA

Fellowship in Societies, Membership in Journal Editorial Committees

Professional Societies:

2000 Member, Endocrine Society, USA
2000 -2007 Member, American Association of Clinical Endocrinologists
2002-2007 Member, International Society for Clinical Densitometry
2003-2007 Member, The American College of Clinical Nutrition
2004-2007 Member, American Federation Medical Research
2005-2007 Member, Boston Obesity Nutrition Research Center
2005- Member, Hellenic Endocrine Society
2006- Athens Medical Society

Major Committee Assignments:

2001-2007 Board Member, New England Hellenic Medical and Dental Society
2010- Board Member for Pharmacy regulation Committee at the Hygeia Hospital, Athens, Greece

Work Experience

Koutkia P., C.A Apovian. Nutrition support in the critically ill diabetic patient. In: Nutri-tional considerations in the intensive care unit.(1st edition) Shikora SA, Martindale RG (eds). The American Society for Parenteral and Enteral Nutrition (A.S.P.E.N) and Kendall Hunt Publishing. Ch15, pp:175-185; 2002.
Koutkia P., C.A Apovian, GL. Blackburn. Nutrition Support. In: Principles and Practice of Palliative Care and Supportive Oncology (2nd edition). Berger AM, Portenoy RK, Weiss-man DE (eds). Williams and Wilkins, Philadelphia, PA pp:933-955; 2002.
Koutkia P., R.Y Wang. Electroplaters. In: Occupational, Industrial, and Environmental Toxicology (2nd edition). Greenberg M, Hamilton R, Phillips S (eds). Mosby, MO 2003

Educational Material:

Koutkia P. Entrance left: The endocrinologist. AIDS Clinical Care 104. (NEJM ) January 4th, 2006.
Koutkia P., Grinspoon S. Physiologic Regulation and Potential Utility of Growth Hormone in HIV Lipodystrophy. Neuroendocrine Center Bulletin, MGH, vol 10, issue 1, Spring/Summer 2004.
Koutkia P., R.Y. Wang. Case Studies in Environmental Medicine. Radiation exposure from Iodine 131. Published by U.S Department of Health and human Services. Agency for Toxic Substances and Disease Registry (ATSDR)/Center for Disease Control (CDC), Division of Health Education and Promotion. November 2002.
Koutkia P., E. Mylonakis, T. Flanigan. Enterohemorrhagic Escherichia coli O157:H7 [Pa-tient information handout] Am Fam Physician 56 (3):859-61;1997.

Honors & Awards

1990-1993 Mavrocordatos Scholarship, National University of Athens Medical School, Athens, Greece
2002 Eleni Gatzoyiannis Scholarship, Boston University, Boston, MA
2003 Genentech Clinical Fellows Travel Grant Award
2003 Recipient, Travel Award, Boston Obesity Nutrition Research Center
2004 Genentech Clinical Fellows Travel Grant Award (Endocrine Society)
2006 Junior Physician Investigator Award, American Federation Medical Research
2010 1st Business prize MIG award, Hygeia Hospital, Greece

Books

Koutkia P., C.A Apovian. Nutrition support in the critically ill diabetic patient. In: Nutri-tional considerations in the intensive care unit.(1st edition) Shikora SA, Martindale RG (eds). The American Society for Parenteral and Enteral Nutrition (A.S.P.E.N) and Kendall Hunt Publishing. Ch15, pp:175-185; 2002.
Koutkia P., C.A Apovian, GL. Blackburn. Nutrition Support. In: Principles and Practice of Palliative Care and Supportive Oncology (2nd edition). Berger AM, Portenoy RK, Weiss-man DE (eds). Williams and Wilkins, Philadelphia, PA pp:933-955; 2002.
Koutkia P., R.Y Wang. Electroplaters. In: Occupational, Industrial, and Environmental Toxicology (2nd edition). Greenberg M, Hamilton R, Phillips S (eds). Mosby, MO 2003
E.Mylonakis, Koutkia P. Research during residency [letter] JAMA 281(22):2089, 1999.
Koutkia P, E. Mylonakis, S. Rounds, A. Erickson. Leucocytoclastic vasculitis: an update for the physician. Scand J Rheumatol 30:315-322;2001.
Mylonakis E, Koutkia P, Grinspoon S. Diagnosis and treatment of androgen deficiency in human immunodeficiency virus-infected men and women. Clin Inf Dis. 2001; 33:857-64.
Sundaram A., Koutkia P., C.A. Apovian. Nutritional management of short bowel syn-drome in adults. J Clin Gastroenterol 34:207-20; 2002.
Koutkia P, Grinspoon S. HIV-Associated Lipodystrophy: Pathogenesis, Prognosis, Treat-ment and Controversies. Annu Rev Med. 2004;55:303-17.

Reading materials and Case-reports:

Koutkia P, T. Chen, MF. Holick. Vitamin D intoxication associated with an-over-the coun-ter supplement.[letter] N Engl J Med 345:66-67; 2001.
Koutkia P., T. Chen, L. Zhiren, MF. Holick. Treatment of hypocalcemia due to Crohn’s disease with Ultraviolet B irradiation. Gastroenterology 121:1485-1488; 2001.
Koutkia P., J. Safer. Adrenal metastasis secondary to papillary thyroid carcinoma. Thyroid 11:1077-1079; 2001.
Koutkia P., H. Safran, C. Kahn. Metastatic carcinoma mimicking primary thyroid cancer. RI Med Health 84:204-206; 2001.

Recent Publications

Tangpricha V. Koutkia P. Rieke SM. Chen TC. Perez AA. Holick MF. Fortification of orange juice with vitamin D: a novel approach for enhancing vitamin D nutritional health. Am J Clin Nutr 77(6):1478-83, 2003.
Koutkia P, Canavan B, Johnson ML, DePaoli A, Grinspoon S. Characterization of Leptin Pulse Dynamics and Relationship to Fat Mass, Growth Hormone, Cortisol and Insulin in Human Physiology. Am J Phys Endocrinol and Metabol 285(2):E372-9;2003.
Koutkia P, Meininger G, Canavan B, Breu J, Grinspoon S. Metabolic Regulation of Growth Hormone by Free Fatty Acids, Somatostatin and Ghrelin in HIV Lipodystrophy. Am J Physiol Endocrinol Metab. 2004 Feb;286(2):E296-303.
Koutkia P, Canavan B, Breu J, Johnson M.L, DePaoli A, and Grinspoon S. Relation of Leptin Pulse Dynamics to Fat Distribution in HIV–Infected Patients. Am J Clin Nutr. 2004 Jun;79(6):1103-9.
Bernstein LE, Koutkia P, Linquist K, Breu J, Canavan B, Grinspoon S. Acute Regulation of Adiponectin by Free Fatty Acids. Metabolism. 2004 Jun;53(6):790-3.
Koutkia P, Canavan B, Breu J. Johnsonn ML, Grinspoon S. Nocturnal Ghrelin Pulsatility and Response to Growth Hormone Secretagogues in Healthy Men. Am J Physiol Endocrinol Metab. 2004 Sep;287(3):E506-12.
Koutkia P., Canavan B., Breu J, Torriani M., Kissko J., Grinspoon S. The Use of
Growth Hormone Releasing Hormone (GHRH) in HIV Lipodystrophy: A Randomized Placebo-Controlled Trial. JAMA 2004 Jul 14;292(2):210-8.
Schurgin S, Canavan B, Koutkia P, DePaoli A, Grinspoon S. Endocrine and Metabolic Effects of Physiologic r-metHuLeptin Administration During Acute Caloric Deprivation in Normal Weight Women. JCEM 2004 Nov; 89(11): 5402-9.
Koutkia P., Canavan B., Breu J, Grinspoon S. Growth Hormone Responses to GHRH-Arginine Testing in HIV Lipodystrophy . JCEM 2005 Jan;90(1):32-8.
Koutkia P, Canavan B, Breu J, Grinspoon S. Effects of Growth Hormone Releasing Hormone on Bone Turnover in HIV- infected Men with Fat Accumulation. J Clin Endocrinol Metab. 2005 Apr;90(4):2154-60.
Falutz J., Allas S., Kotler D., Thompson M., Koutkia P., Albu J., Trottier B., Routy JP., Cote P., Abribat T, Grinspoon S. A placebo-controlled, dose-ranging study of a growth hormone releasing factor in HIV-infected patients with abdominal fat accumulation. AIDS 2005 Aug 12;19(12):1279-1287.
Koutkia P, Schurgin S, Berry J, Breu J, Lee H, Klibanski A, Grinspoon S. “Reciprocal Changes in Endogenous Ghrelin and Growth Hormone During Fasting in Healthy Women”. Am J Physiol Endocrinol Metab.2005 Nov;289(5):E814-22. Epub 2005 Jun 21.
Canavan B, Salem RO, Schurgin S, Koutkia P, Lipinska I, Laposata M, and Grinspoon S. Effects of Physiologic Leptin Administration on Markers of Inflammation, Platelet Activation and Platelet Aggregation During Caloric Deprivation. J Clin Endocrinol Metab. 2005 Oct;90(10):5779-85.
Koutkia P, Berry J, Eaton K, Breu J, Grinspoon S. Increased Adrenal Androgen Secretion With Inhibition of 11-B hydroxylase in HIV-Infected Women. Am J Physiol Endocrinol Metab 2005; Nov 22.
Koutkia P, Eaton K, You SM, Breu J, Grinspoon S. Growth Hormone Secretion Among HIV Infected Patients: Effects of Gender, Race and Fat Distribution. AIDS. 2006 Apr 4;20(6):855-62.
Lo J, You SM, Canavan B, Liebau J, Beltrani G, Koutkia P, Hemphill L, Lee H. Grinspoon S. Low-dose physiological growth hormone in patients with HIV and ab-dominal fat accumulation: a randomized controlled trial. JAMA. 2008 Aug 6;300(5):509-19.